Optimize

Genomic Sequencing

Accelerate strain development with in-house genomic sequencing and bioinformatics

We recommend leveraging our in-house Oxford Nanopore sequencing capabilities to gain comprehensive genomic insights into your production strains. Especially for library approaches, genomic characterization is essential to identify top-performing candidates, determine copy number variations, map integration loci, and understand the genetic basis of strain performance.

We apply Oxford Nanopore sequencing to correlate genomic modifications with changes in expression levels, providing a deeper understanding of how genetic engineering strategies impact cellular performance. These insights enable more informed decision-making and support targeted strain optimization. By combining state-of-the-art sequencing technology with our dedicated in-house bioinformatics pipeline, we can rapidly process, analyze, and interpret sequencing data. The result is a significantly faster and more efficient build-test-learn cycle, enabling accelerated strain development, improved engineering success rates, and faster progression from screening to production-ready strains.

  • Oxford Nanopore-based whole-genome sequencing
  • gDNA preparation, sequencing, and bioinformatics analysis
  • Rapid in-house data generation and interpretation
  • Integration locus identification
  • Copy number analysis
  • Correlation of genomic modifications with expression levels
  • Data-driven optimization of design-build-test-learn cycles
  • Genetic stability assessment
  • Regulatory-supporting genomic documentation