Optimize

Process development

Process development is a key step in maximizing the full production potential of a newly developed strain.

To maximize protein yield, productivity, and process robustness, we combine strain development with tailored fed-batch process optimization. Using a structured Design of Experiments (DoE) approach, we efficiently identify optimal cultivation conditions and support scale-up from laboratory to production scale.

  • Integrated strain and process development for a seamless transition from clone selection to production.

  • Tailored fed-batch optimization to maximize protein yield, productivity, and process performance.

  • Design of Experiments (DoE) methodology for efficient optimization of multiple process parameters in parallel.

  • Data-driven parameter selection based on in-house expertise, product-specific knowledge, and scientific literature.

  • Small-scale media screening to identify optimal medium compositions and critical nutrient requirements.

  • Targeted optimization of trace metal composition for proteins and enzymes sensitive to micronutrient availability.

  • Scale-up support and bioreactor cultivation through trusted partners across different production scales.